Pseudomonas aeruginosa and microbial keratitis
نویسندگان
چکیده
منابع مشابه
Serrated Margins in Pseudomonas aeruginosa Keratitis
PURPOSE To describe 3 cases of culture-positive P. aeruginosa keratitis, who presented with a focus having serrated margins. METHODS Observational case report. RESULTS Three cases wearing contact lenses complained of symptoms such as pain, redness, and a decrease in vision. Slit-lamp biomicroscopic examination revealed a focus with serrated margins in all cases. The patients underwent corne...
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PURPOSE To compare the proteomic profile of a clinical isolate of Pseudomonas aeruginosa (P. aeruginosa) obtained from an infected cornea of a contact lens wearer and the laboratory strain P. aeruginosa ATCC 10145. METHODS Antibiotic sensitivity, motility, biofilm formation, and virulence tests were performed using standard methods. Whole protein lysates were analyzed with liquid chromatograp...
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Pseudomonas aeruginosa is a ubiquitous bacterium that causes opportunistic infections in a range of host tissues and organs. Infections by P. aeruginosa are difficult to treat and hence there is interest in the development of effective therapeutics. One of the key mechanisms that P. aeruginosa uses to control the expression of many virulence factors is the N-acylated homoserine lactone (AHL) re...
متن کاملOral vaccination and multivalent vaccine against Pseudomonas aeruginosa keratitis.
Active immunization against Pseudomonas aeruginosa keratitis and systemic disease in mice was studied. In the first series of experiments, monovalent vaccine, administered orally or intraperitoneally, protected against subsequent corneal and intraperitoneal challenge with the homologous strain of P. aeruginosa; however, oral administration of vaccine elicited less protection than intraperitonea...
متن کاملPseudomonas aeruginosa exotoxin A and keratitis in mice.
PURPOSE To determine the importance of Pseudomonas aeruginosa exotoxin A (ETA) as a virulence factor in corneal disease. METHODS Isogenic mutants deficient in ETA were constructed in P. aeruginosa strains PAO1 and ATCC 19660 by allelic exchange and then evaluated for virulence in a mouse model of bacterial keratitis. The effect of ETA on adherence to scarified corneal epithelium was assessed ...
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ژورنال
عنوان ژورنال: Journal of Medical Microbiology
سال: 2020
ISSN: 0022-2615,1473-5644
DOI: 10.1099/jmm.0.001110